Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | IL6 | P05231 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17488105 | 0.90 | RAB9A (0.41) | RAB9ASMN1; SMN2TP53LMNAHTT | |
| SCHEMBL17488159 | 0.90 | RAB9A (0.41) | RAB9ASMN1; SMN2TP53LMNAHTT | |
| SCHEMBL17488013 | 0.88 | RAB9A (0.39) | RAB9ASMN1; SMN2TP53LMNAHTT | |
| SCHEMBL17488103 | 0.88 | SCN9A (0.47) | RAB9ASMN1; SMN2TP53SCN9AKDR | |
| SCHEMBL17487504 | 0.85 | RAB9A (0.41) | RAB9ASMN1; SMN2TP53LMNAHTT | |
| SCHEMBL17488018 | 0.84 | RAB9A (0.43) | RAB9ASMN1; SMN2TP53LMNAHTT | |
| SCHEMBL17487495 | 0.83 | RAB9A (0.42) | RAB9ASMN1; SMN2TP53LMNAHTT | |
| SCHEMBL17487676 | 0.83 | CYP3A4 (0.36) | RAB9ASMN1; SMN2TP53LMNAIL6 | |
| SCHEMBL17487996 | 0.83 | RAB9A (0.45) | RAB9ASMN1; SMN2TP53LMNAHTT | |
| SCHEMBL17487715 | 0.83 | KDR (0.36) | RAB9ASMN1; SMN2TP53GFERSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |