Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 5/20 | 0.33 |
| ▸ | TEK | Q02763 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.30 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17488096 | 0.82 | RAB9A (0.42) | RAF1RIPK1KDRTEKPOLB | |
| SCHEMBL18965789 | 0.82 | ATP1A1 (0.35) | — | |
| SCHEMBL17488338 | 0.82 | SCN9A (0.44) | KDRTEK | |
| SCHEMBL17488324 | 0.80 | IGF1R (0.44) | — | |
| SCHEMBL17488003 | 0.80 | SCN9A (0.37) | RAF1RIPK1KDRTEK | |
| SCHEMBL17487839 | 0.77 | RAB9A (0.33) | RAF1RIPK1KDRTEKPOLB | |
| SCHEMBL17487817 | 0.77 | RIPK1 (0.34) | RIPK1KDRTEKPOLBLMNA | |
| SCHEMBL17487481 | 0.74 | RAB9A (0.39) | RAF1RIPK1KDRTEKLMNA | |
| SCHEMBL17488236 | 0.74 | RAB9A (0.42) | KDRTEKPOLBCSNK1A1CSNK1D | |
| SCHEMBL17488301 | 0.73 | CYP3A4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |