Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19624543 | 0.93 | CHEK2 (0.42) | L3MBTL1NR1I2CYP11B1CYP11B2PDK2 | |
| SCHEMBL19157196 | 0.89 | PTPN11 (0.46) | L3MBTL1CYP11B1CYP11B2ALDH1A1DRD2 | |
| SCHEMBL19020168 | 0.88 | TSHR (0.44) | L3MBTL1FFAR4ALDH1A1MAPK1SYK | |
| SCHEMBL17485686 | 0.85 | PTPN11 (0.49) | L3MBTL1NR1I2ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL17485688 | 0.85 | ALDH2 (0.51) | L3MBTL1PDK2ALDH1A1RECQLMAOA | |
| SCHEMBL24727509 | 0.84 | PTPN11 (0.52) | PDK2PTPN11ALDH2 | |
| SCHEMBL19803990 | 0.83 | TDP1 (0.43) | L3MBTL1CYP11B1CYP11B2FFAR4CA1 | |
| SCHEMBL17488402 | 0.83 | ALOX5AP (0.47) | CYP11B1CYP11B2PDK2FFAR4MAOA | |
| SCHEMBL18308824 | 0.81 | ALDH1A1 (0.44) | L3MBTL1NR1I2ALDH1A1RECQLMAPK1 | |
| SCHEMBL18644007 | 0.80 | ALDH1A1 (0.56) | L3MBTL1NR1I2FFAR4ALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938229-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2018-04-10 | — | — | US | disclosed |
| US-20160032189-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160032189-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | VCL, ILK, LCP1 | L3MBTL1 1100/4885NR1I2 4587/4885CYP11B1 4179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.