Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK3 | P27361 | 5/20 | 0.58 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.56 |
| ▸ | LY6K | Q17RY6 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 3/20 | 0.51 |
| ▸ | ITK | Q08881 | 2/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | JAK1 | P23458 | 1/20 | 0.51 |
| ▸ | TYK2 | P29597 | 1/20 | 0.51 |
| ▸ | JAK3 | P52333 | 1/20 | 0.51 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.50 |
| ▸ | FLT1 | P17948 | 2/20 | 0.48 |
| ▸ | FLT4 | P35916 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.44 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17489872 | 0.89 | LY6K (0.53) | MAPK3MAP3K7LY6KEGFRITK | |
| SCHEMBL17489866 | 0.81 | MAP3K7 (0.59) | MAPK3MAP3K7EGFRITKJAK2 | |
| SCHEMBL23685817 | 0.77 | ABL1 (0.56) | LY6KEGFRITKL3MBTL3FLT1 | |
| SCHEMBL17489625 | 0.77 | SORT1 (0.50) | LY6KEGFRITKL3MBTL3FLT1 | |
| SCHEMBL18857464 | 0.75 | MAPK3 (0.89) | MAPK3MAP3K7LY6KEGFRITK | |
| SCHEMBL15938348 | 0.74 | MAPK3 (0.89) | MAPK3MAP3K7EGFRITKJAK2 | |
| SCHEMBL15938821 | 0.73 | MAPK3 (1.00) | MAPK3MAP3K7LY6KEGFRITK | |
| SCHEMBL23880018 | 0.72 | PKM (0.63) | LY6KL3MBTL3PKMF2PRSS1 | |
| SCHEMBL13165940 | 0.72 | EGFR (0.81) | MAPK3MAP3K7EGFRITKJAK2 | |
| SCHEMBL18737564 | 0.72 | EGFR (0.81) | MAPK3MAP3K7EGFRITKJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160031826-A1 | Substituted Heterocyclic Compounds for Treating or Preventing Viral Infections | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160031826-A1 | Substituted Heterocyclic Compounds for Treating or Preventing Viral Infections | HAVCR2, DDX5, DPYD | MAPK3 3523/4885MAP3K7 3395/4885LY6K 2675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.