SCHEMBL1749189

SCHEMBL1749189

Cc1ccc(S(=O)(=O)n2c(I)cc3c(Cl)c(F)cnc32)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 5/20 0.37
LMNA P02545 2/20 0.37
ALDH3A1 P30838 2/20 0.37
HTT P42858 2/20 0.37
NOD1 Q9Y239 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
POLB P06746 1/20 0.37
TP53 P04637 1/20 0.37
PKM P14618 2/20 0.35
CCKAR P32238 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
MAPT P10636 2/20 0.33
HSD11B1 P28845 1/20 0.33
ABL1 P00519 1/20 0.33
BCR P11274 1/20 0.33
CXCL8 P10145 1/20 0.33
GAA P10253 1/20 0.33
NOD2 Q9HC29 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16042802 0.88 SRC (0.39) PTGDR2LMNAALDH3A1HTTNOD1
SCHEMBL17535141 0.88 ALDH3A1 (0.39) PTGDR2LMNAALDH3A1HTTNOD1
SCHEMBL1356567 0.88 HTT (0.39) PTGDR2LMNAALDH3A1HTTNOD1
SCHEMBL20536259 0.86 ABL1 (0.42) PTGDR2LMNAALDH3A1HTTNOD1
SCHEMBL28563225 0.82 MEN1 (0.39) PTGDR2LMNAALDH3A1HTTNOD1
SCHEMBL5413878 0.79 NOD1 (0.39) PTGDR2LMNAALDH3A1HTTNOD1
SCHEMBL1749021 0.79 PTGDR2 (0.44) PTGDR2LMNAALDH3A1HTTNOD1
SCHEMBL16977994 0.78 PTGDR2 (0.40) PTGDR2LMNAALDH3A1HTTL3MBTL1
SCHEMBL2997249 0.78 PTGDR2 (0.34) PTGDR2LMNAHTTNOD1L3MBTL1
Hydrochloric Acid SCHEMBL29431232 0.77 HTR6 (0.35) PTGDR2LMNAALDH3A1HTTNOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026087613-A1 3-AZA-BICYCLO[3.3.0]OCTANE COMPOUNDS, PREPARATION AND THERAPEUTIC USES THEREOF SANOFI (FR) 2026-04-30 WO disclosed
US-20260028346-A1 BTK DEGRADER AND USE THEREOF ASCENTAGE PHARMA SUZHOU CO LTD (CN) 2026-01-29 US disclosed
US-20260028345-A1 BTK DEGRADER AND USE THEREOF ASCENTAGE PHARMA SUZHOU CO LTD (CN) 2026-01-29 US disclosed
US-7968566-B2 Pyrrolo(2,3-b) pyridine derivatives, the preparation and the pharmaceutical use thereof in the form of kinase inhibitors AVENTIS PHARMA S.A. (FR) 2011-06-28 US disclosed
US-20090233956-A1 NOVEL PYRROLO(2,3-b) PYRIDINE DERIVATIVES, THE PREPARATION AND THE PHARMACEUTICAL USE THEREOF IN THE FORM OF KINASE INHIBITORS AVENTIS PHARMA S.A. (FR) 2009-09-17 US disclosed
US-7528147-B2 Pyrrolo (2,3-b)pyridine derivatives, the preparation and the pharmaceutical use thereof in the form of kinase inhibitors AVENTIS PHARMA S.A. (FR) 2009-05-05 US disclosed
US-20070093480-A1 Novel pyrrolo (2,3-b)pyridine derivatives, the preparation and the pharmaceutical use thereof in the form of kinase inhibitors AVENTIS PHARMA S.A. (FR) 2007-04-26 US disclosed
CN-1950083-A Novel pyrrolo (2,3-b)pyridine derivatives, the preparation and the pharmaceutical use thereof in the form of kinase inhibitors AVENTIS PHARMA SA (FR) 2007-04-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028345-A1 BTK DEGRADER AND USE THEREOF BTK, SYK, TEC PTGDR2 2232/4885LMNA 4401/4885ALDH3A1 4691/4885
US-20090233956-A1 NOVEL PYRROLO(2,3-b) PYRIDINE DERIVATIVES, THE PREPARATION AND THE PHARMACEUTICAL USE THEREOF IN THE FORM OF KINASE INHIBITORS MAP3K19, MAP4K2, MAP3K1 PTGDR2 806/4885LMNA 3851/4885ALDH3A1 2782/4885
US-20260028346-A1 BTK DEGRADER AND USE THEREOF BTK, SYK, LYN PTGDR2 2360/4885LMNA 4346/4885ALDH3A1 4716/4885
US-20070093480-A1 Novel pyrrolo (2,3-b)pyridine derivatives, the preparation and the pharmaceutical use thereof in the form of kinase inhibitors MAP3K19, MAP4K2, MAP3K1 PTGDR2 806/4885LMNA 3851/4885ALDH3A1 2782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.