Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14741341 | 0.97 | HTR1A (0.31) | HTR1ASLC6A4 | |
| SCHEMBL14746207 | 0.85 | MAOA (0.32) | MAOB | |
| SCHEMBL14745861 | 0.85 | MAOA (0.32) | MAOB | |
| SCHEMBL14746187 | 0.83 | MAOA (0.32) | MAOB | |
| SCHEMBL17495137 | 0.83 | — | — | |
| SCHEMBL14741507 | 0.82 | — | — | |
| SCHEMBL17494908 | 0.82 | — | — | |
| SCHEMBL17494905 | 0.82 | — | — | |
| SCHEMBL14745773 | 0.81 | — | — | |
| SCHEMBL14745447 | 0.81 | DUT (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016025932-A1 | SUBSTITUTED POLYCYCLIC ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-02-18 | — | — | WO | disclosed |