Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 9/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17495001 | 0.79 | MEN1 (0.34) | HTR6PPARGUSP2ALDH1A1LMNA | |
| SCHEMBL17498069 | 0.78 | USP2 (0.40) | HTR6USP2ALDH1A1LMNAGAA | |
| SCHEMBL17494988 | 0.77 | HDAC1 (0.36) | HDAC1HDAC6HTR6PPARGUSP2 | |
| SCHEMBL17495176 | 0.74 | USP2 (0.40) | USP2ALDH1A1GAAMAPTHTT | |
| SCHEMBL17494961 | 0.74 | HTR6 (0.45) | SLC1A3SLC1A2SLC1A1HTR6PPARG | |
| SCHEMBL14745702 | 0.66 | USP2 (0.39) | USP2GAAMAPTHTT | |
| SCHEMBL9372377 | 0.65 | CPT1A (0.54) | SLC1A3SLC1A2SLC1A1HDAC1HDAC6 | |
| SCHEMBL1778140 | 0.65 | HDAC1 (0.60) | HDAC1HDAC6HTR6PPARGHDAC3 | |
| SCHEMBL30955477 | 0.65 | CPT1A (0.54) | SLC1A3SLC1A2SLC1A1HDAC1HDAC6 | |
| SCHEMBL14746175 | 0.64 | USP2 (0.37) | USP2GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016025932-A1 | SUBSTITUTED POLYCYCLIC ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-02-18 | — | — | WO | disclosed |