Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17495144 | 0.78 | SLC1A3 (0.35) | USP2HTR6GAAHTTLMNA | |
| SCHEMBL17498206 | 0.75 | HTR6 (0.39) | HTR6TP53KDM4ELMNAMAPT | |
| SCHEMBL17498192 | 0.73 | HTR6 (0.44) | HTR6KDM4EHTTMMP2ALOX5 | |
| SCHEMBL30825266 | 0.73 | HTR6 (0.44) | HTR6KDM4EHTTMMP2ALOX5 | |
| SCHEMBL17498117 | 0.72 | USP2 (0.38) | USP2KDM4EGAAHTTLMNA | |
| SCHEMBL17498084 | 0.71 | BRD4 (0.32) | USP2KDM4ELMNAMAPTMEN1 | |
| SCHEMBL17498048 | 0.70 | TRIM24 (0.41) | HTR6TRIM24TRIM33MMP2MAPT | |
| SCHEMBL31065105 | 0.70 | HTR6 (0.42) | HTR6KDM4EGAAALOX5MAPT | |
| SCHEMBL21643762 | 0.70 | HTR6 (0.42) | HTR6KDM4EGAAALOX5MAPT | |
| SCHEMBL17498163 | 0.68 | USP2 (0.45) | USP2KDM4EGAAHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016025933-A2 | SUBSTITUTED POLYCYCLIC ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-02-18 | — | — | WO | disclosed |
| WO-2016025933-A2 | SUBSTITUTED POLYCYCLIC ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-02-18 | — | — | WO | disclosed |