SCHEMBL17499142

SCHEMBL17499142

CC(=Nc1ccccc1O[SiH](C)C)c1cncn1C

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.32
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16098220 0.85 ALDH1A1 (0.42) IDO1ALDH1A1LMNAMAPTHSD17B10
SCHEMBL16102259 0.84 HPGDS (0.32) IDO1
SCHEMBL17499678 0.83 IDO1 (0.33) IDO1ALDH1A1LMNAMAPTHSD17B10
SCHEMBL17499822 0.78 HTT (0.34) ALDH1A1LMNAMAPTHSD17B10
SCHEMBL17499760 0.76 ALDH1A1 (0.30) ALDH1A1LMNAMAPTHSD17B10
SCHEMBL17499420 0.76 ALDH1A1 (0.30) ALDH1A1LMNAMAPTHSD17B10
SCHEMBL17499787 0.76 ALDH1A1 (0.33) ALDH1A1LMNAMAPTHSD17B10
SCHEMBL17499223 0.74 ALDH1A1 (0.30) ALDH1A1LMNAMAPTHSD17B10
SCHEMBL17499253 0.74 NAMPT (0.34) ALDH1A1LMNAMAPTHSD17B10
SCHEMBL17499295 0.74 SMN1; SMN2 (0.34) ALDH1A1LMNAMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2969593-B1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES BRIDGESTONE CORP (JP) 2020-11-04 EP disclosed
US-9850328-B2 Polymers functionalized with heterocyclic imines BRIDGESTONE CORPORATION (JP) 2017-12-26 US disclosed
US-20160039958-A1 Polymers Functionalized With Heterocyclic Imines BRIDGESTONE CORPORATION (JP) 2016-02-11 US disclosed