Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | FGB | P02675 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.32 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16101893 | 0.85 | ALDH1A1 (0.42) | NAMPTKMT2AHSD17B10RAB9AMEN1 | |
| SCHEMBL17499121 | 0.84 | SMN1; SMN2 (0.40) | NAMPTKMT2AHSD17B10TSHRRAB9A | |
| SCHEMBL17499209 | 0.83 | NAMPT (0.35) | NAMPTKMT2AHSD17B10TSHRRAB9A | |
| SCHEMBL17499527 | 0.78 | KDM4E (0.37) | KMT2AHSD17B10RAB9AMEN1KDM4E | |
| SCHEMBL17499126 | 0.77 | KDM4E (0.50) | KMT2ARAB9AMEN1KDM4EALDH1A1 | |
| SCHEMBL17499760 | 0.76 | ALDH1A1 (0.30) | HSD17B10ALDH1A1LMNAMAPT | |
| SCHEMBL17499420 | 0.76 | ALDH1A1 (0.30) | HSD17B10ALDH1A1LMNAMAPT | |
| SCHEMBL17499259 | 0.75 | TSHR (0.36) | KMT2AHSD17B10TSHRRAB9AMEN1 | |
| SCHEMBL17499822 | 0.75 | HTT (0.34) | NAMPTKMT2AHSD17B10RAB9AKDM4E | |
| SCHEMBL17499142 | 0.74 | IDO1 (0.32) | HSD17B10ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |