Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28039883 | 0.99 | SMN1; SMN2 (0.35) | SMN1; SMN2RAB9ANPC1ALDH1A1GAA | |
| SCHEMBL17499769 | 0.86 | SMN1; SMN2 (0.44) | SMN1; SMN2RAB9ANPC1ALDH1A1GAA | |
| SCHEMBL17499226 | 0.85 | SMN1; SMN2 (0.37) | SMN1; SMN2RAB9ANPC1ALDH1A1GAA | |
| SCHEMBL17499296 | 0.85 | ATM (0.38) | SMN1; SMN2RAB9ANPC1ALDH1A1GAA | |
| SCHEMBL17499500 | 0.83 | RAB9A (0.34) | SMN1; SMN2RAB9ANPC1ALDH1A1GAA | |
| SCHEMBL28039913 | 0.82 | RAB9A (0.34) | SMN1; SMN2RAB9ANPC1ALDH1A1GAA | |
| SCHEMBL16102431 | 0.79 | MAPT (0.31) | ALDH1A1MAPT | |
| SCHEMBL28823563 | 0.78 | MAPT (0.31) | ALDH1A1MAPT | |
| SCHEMBL16097793 | 0.76 | — | — | |
| SCHEMBL16097563 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |