Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16101313 | 0.86 | NOS3 (0.42) | ATMRAB9ASMN1; SMN2NPC1GAA | |
| SCHEMBL17499152 | 0.85 | SMN1; SMN2 (0.35) | ATMRAB9ASMN1; SMN2NPC1GAA | |
| SCHEMBL16101305 | 0.84 | RAB9A (0.37) | ATMRAB9ASMN1; SMN2NPC1GAA | |
| SCHEMBL28039883 | 0.84 | SMN1; SMN2 (0.35) | ATMRAB9ASMN1; SMN2NPC1GAA | |
| SCHEMBL17499214 | 0.84 | ATM (0.39) | ATMRAB9ASMN1; SMN2NPC1GAA | |
| SCHEMBL17499130 | 0.80 | NPC1 (0.32) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL17499259 | 0.77 | TSHR (0.36) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL17499295 | 0.76 | SMN1; SMN2 (0.34) | RAB9ASMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL17499760 | 0.75 | ALDH1A1 (0.30) | ALDH1A1MAPTLMNAHSD17B10 | |
| SCHEMBL17499692 | 0.75 | TDP1 (0.32) | ALDH1A1MAPTLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |