SCHEMBL17499159

SCHEMBL17499159

Cc1cnn(C)c1CC=Nc1ccccc1O[Si](C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
BLM P54132 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16101292 0.88 ALDH1A1 (0.37) KDM4EALDH1A1BLM
SCHEMBL17499272 0.84 KDM4E (0.31) KDM4EALDH1A1BLM
SCHEMBL17499427 0.83 KDM4E (0.36) KDM4EALDH1A1BLM
SCHEMBL17499386 0.79 KMT2A (0.30)
SCHEMBL17499757 0.79 ALDH1A1 (0.34) KDM4EALDH1A1BLM
SCHEMBL17499756 0.79 ALDH1A1 (0.34) KDM4EALDH1A1BLM
SCHEMBL17499194 0.78
SCHEMBL17499429 0.77 KDM1A (0.34) KDM4EALDH1A1
SCHEMBL17499180 0.74 MEN1 (0.30)
SCHEMBL17499618 0.74 PPARG (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2969593-B1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES BRIDGESTONE CORP (JP) 2020-11-04 EP disclosed
US-9850328-B2 Polymers functionalized with heterocyclic imines BRIDGESTONE CORPORATION (JP) 2017-12-26 US disclosed
US-20160039958-A1 Polymers Functionalized With Heterocyclic Imines BRIDGESTONE CORPORATION (JP) 2016-02-11 US disclosed