SCHEMBL17499386

SCHEMBL17499386

Cn1nccc1CC=Nc1ccccc1O[Si](C)(C)C

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16100418 0.88 ALDH1A1 (0.38) KMT2AL3MBTL1
SCHEMBL17499715 0.85
SCHEMBL17499211 0.80 PDE4A (0.32)
SCHEMBL17499159 0.79 KDM4E (0.32)
SCHEMBL17499427 0.79 KDM4E (0.36)
SCHEMBL17499540 0.78 MEN1 (0.32) KMT2A
SCHEMBL17499429 0.77 KDM1A (0.34) KMT2AL3MBTL1
SCHEMBL17499580 0.77 MEN1 (0.38) KMT2A
SCHEMBL17499169 0.77 KMT2A (0.35) KMT2A
SCHEMBL17499173 0.77 KMT2A (0.35) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2969593-B1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES BRIDGESTONE CORP (JP) 2020-11-04 EP disclosed
US-9850328-B2 Polymers functionalized with heterocyclic imines BRIDGESTONE CORPORATION (JP) 2017-12-26 US disclosed
US-20160039958-A1 Polymers Functionalized With Heterocyclic Imines BRIDGESTONE CORPORATION (JP) 2016-02-11 US disclosed