Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8150568 | 0.96 | GAA (0.43) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL25312474 | 0.96 | GAA (0.43) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL2285210 | 0.88 | GAA (0.43) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL11163358 | 0.86 | GAA (0.55) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL29032352 | 0.86 | GAA (0.41) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL7606970 | 0.84 | GAA (0.50) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL31373010 | 0.84 | CES2 (0.44) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL6665142 | 0.84 | GAA (0.52) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL27949724 | 0.83 | ALDH1A1 (0.40) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL21069919 | 0.82 | GAA (0.50) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119162703-A | Biodegradable polylactic acid-based home textile fabric and preparation method thereof | 烟台明远创意生活科技股份有限公司 | 2024-12-20 | — | — | CN | claimed |
| CN-118126764-A | Lubricating oil for restoring expansion force of piston ring and having no oil dirt and preparation method thereof | 普朗克量子科技(天津)有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-102464580-B | The preparation of halogen ethoxyacetic acid and ester thereof | CHONGQING HUABANGSHENGKAI PHARM. Co.,Ltd. (CN) | 2015-07-29 | — | — | CN | claimed |
| CN-103373973-A | Novel synthetic process for levocetirizine and key intermediates | HUNAN JIUDIAN PHARMACEUTICAL CO LTD | 2013-10-30 | — | — | CN | claimed |
| CN-103044356-A | New method for synthesizing levocetirizine and key intermediate thereof | HUNAN JIUDIAN PHARMACEUTICAL CO LTD | 2013-04-17 | — | — | CN | claimed |
| CN-103044355-A | Key intermediate for synthesizing levocetirizine and preparation method thereof | HUNAN JIUDIAN PHARMACEUTICAL CO LTD | 2013-04-17 | — | — | CN | claimed |
| US-20250320195-A1 | TETRAHYDRONAPHTHALENE AND TETRAHYDROISOQUINOLINE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS | ARVINAS OPERATIONS INC (US) | 2025-10-16 | — | — | US | disclosed |
| EP-4630410-A1 | POLQ INHIBITORS | Astrazeneca AB (SE) | 2025-10-15 | — | — | EP | disclosed |
| US-12414954-B2 | POLQ inhibitors | ASTRAZENECA AB (SE) | 2025-09-16 | — | — | US | disclosed |
| US-20250195530-A1 | POLQ INHIBITORS | ASTRAZENECA AB (SE) | 2025-06-19 | — | — | US | disclosed |
| US-20250136614-A1 | 2,7-SUBSTITUTED PYRROLO[2,1-F][1,2,4]TRIAZINE COMPOUND HAVING PROTEIN KINASE INHIBITORY ACTIVITY | MAGICBULLETTHERAPEUTICS CO., LTD. (KR) | 2025-05-01 | — | — | US | disclosed |
| US-20250034193-A1 | PHENOTHIAZINE DERIVATIVES AND USES THEREOF | CAMP4 THERAPEUTICS CORPORATION | 2025-01-30 | — | — | US | disclosed |
| US-12172981-B2 | Tetrahydronaphthalene and tetrahydroisoquinoline derivatives as estrogen receptor degraders | ARVINAS OPERATIONS, INC. (US) | 2024-12-24 | — | — | US | disclosed |
| US-4378314-A | FOR PENICILLINS AND CEPHALOSPORINS | BRISTOL MYERS COMPANY (US) | 1983-03-29 | — | — | US | disclosed |
| US-4374065-A | PENICILLINS, ANTIBIOTICS | BRISTOL-MYERS COMPANY (US) | 1983-02-15 | — | — | US | disclosed |
| US-4282150-A | CHEMICAL INTERMEDIATES FOR PENICILLINS AND CEPHALOSPORINS | BRISTOL-MYERS COMPANY (US) | 1981-08-04 | — | — | US | disclosed |
| US-4272437-A | PENICILLINS | BRISTOL-MYERS COMPANY (US) | 1981-06-09 | — | — | US | disclosed |
| US-4097496-A | ANTIPROSTAGLANDIN ACTIVITY | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-06-27 | — | — | US | disclosed |
| US-4083990-A | ANTIPROSTAGLANDIN EFFECT | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-04-11 | — | — | US | disclosed |
| US-3984459-A | ANTI-PROSTAGLANDINS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12172981-B2 | Tetrahydronaphthalene and tetrahydroisoquinoline derivatives as estrogen receptor degraders | MDM2, CRBN, VHL | GAA 2975/4885MGAM 4691/4885SI 4712/4885 |
| US-20250136614-A1 | 2,7-SUBSTITUTED PYRROLO[2,1-F][1,2,4]TRIAZINE COMPOUND HAVING PROTEIN KINASE INHIBITORY ACTIVITY | STK25, MAP3K15, MAP3K5 | GAA 3842/4885MGAM 4739/4885SI 3989/4885 |
| US-12414954-B2 | POLQ inhibitors | POLQ, POLG, POLB | GAA 142/4885MGAM 1961/4885SI 2504/4885 |
| US-20250320195-A1 | TETRAHYDRONAPHTHALENE AND TETRAHYDROISOQUINOLINE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS | MDM2, CRBN, VHL | GAA 2975/4885MGAM 4691/4885SI 4712/4885 |
| US-20250195530-A1 | POLQ INHIBITORS | POLQ, POLG, POLB | GAA 142/4885MGAM 1961/4885SI 2504/4885 |
| US-20250034193-A1 | PHENOTHIAZINE DERIVATIVES AND USES THEREOF | RPLP2, RPS2, RPLP1 | GAA 449/4885MGAM 2552/4885SI 4760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.