Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29032352 | 0.98 | GAA (0.41) | CES2GAAMGAMSIMGAM2 | |
| SCHEMBL2285210 | 0.92 | GAA (0.43) | CES2GAAMGAMSIMGAM2 | |
| SCHEMBL21070768 | 0.90 | CES2 (0.52) | CES2GAAMGAMSIMGAM2 | |
| SCHEMBL8988864 | 0.88 | CES2 (0.50) | CES2GAAMGAMSIMGAM2 | |
| SCHEMBL22608736 | 0.86 | GAA (0.44) | CES2GAAMGAMSIMGAM2 | |
| SCHEMBL24882784 | 0.86 | GAA (0.48) | CES2GAAMGAMSIMGAM2 | |
| SCHEMBL9511151 | 0.85 | CES2 (0.62) | CES2GAAMGAMSIMGAM2 | |
| SCHEMBL27658857 | 0.85 | CES2 (0.62) | CES2GAAMGAMSIMGAM2 | |
| SCHEMBL3819694 | 0.85 | CES2 (0.62) | CES2GAAMGAMSIMGAM2 | |
| SCHEMBL1749917 | 0.84 | GAA (0.46) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746969-A1 | HETEROCYCLIC PAD4 INHIBITORS | Bristol-Myers Squibb Company (US) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025024288-A1 | HETEROCYCLIC PAD4 INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-01-30 | — | — | WO | disclosed |