Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 7/20 | 0.39 |
| ▸ | RAB9A | P51151 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 5/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499655 | 0.85 | PLAU (0.33) | KDM4EMAPTGAA | |
| SCHEMBL16096919 | 0.85 | HKDC1 (0.48) | KDM4ENPC1RAB9ASMN1; SMN2AGTR1 | |
| SCHEMBL17499417 | 0.85 | KMT2A (0.38) | KDM4ENPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL17499811 | 0.84 | AGTR1 (0.45) | KDM4ENPC1RAB9ASMN1; SMN2AGTR1 | |
| SCHEMBL28858395 | 0.84 | KMT2A (0.37) | KDM4ENPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL6917834 | 0.83 | KDM4E (0.58) | KDM4ENPC1RAB9ASMN1; SMN2AGTR1 | |
| SCHEMBL5589082 | 0.83 | KDM4E (0.58) | KDM4ENPC1RAB9ASMN1; SMN2AGTR1 | |
| SCHEMBL16097536 | 0.83 | KDM4E (0.45) | KDM4ENPC1RAB9ASMN1; SMN2AGTR1 | |
| SCHEMBL17499126 | 0.82 | KDM4E (0.50) | KDM4ENPC1RAB9ASMN1; SMN2AGTR1 | |
| SCHEMBL5693593 | 0.82 | KDM4E (0.56) | KDM4ENPC1RAB9ASMN1; SMN2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |