SCHEMBL17499231

SCHEMBL17499231

Cc1ccsc1CC=Nc1ccccc1O[SiH](C)C

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
ALDH1A1 P00352 1/20 0.31
RAB9A P51151 2/20 0.31
NPC1 O15118 1/20 0.30
PKM P14618 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16096502 0.85 KEAP1 (0.37) MAPTL3MBTL1ALDH1A1RAB9A
SCHEMBL16098158 0.85
SCHEMBL17499379 0.82 POLB (0.32) ALDH1A1
SCHEMBL17499391 0.79 CYP1A2 (0.35) MAPTL3MBTL1ALDH1A1
SCHEMBL17499752 0.79 RAB9A (0.47) MAPTL3MBTL1ALDH1A1RAB9ANPC1
SCHEMBL17499389 0.75 ALDH1A1 (0.33) ALDH1A1
SCHEMBL17499288 0.74 PPARG (0.30)
SCHEMBL17499800 0.73 CYP2C9 (0.33) MAPT
SCHEMBL17499686 0.73
SCHEMBL16097254 0.73 MEN1 (0.38) MAPTL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2969593-B1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES BRIDGESTONE CORP (JP) 2020-11-04 EP disclosed
US-9850328-B2 Polymers functionalized with heterocyclic imines BRIDGESTONE CORPORATION (JP) 2017-12-26 US disclosed
US-20160039958-A1 Polymers Functionalized With Heterocyclic Imines BRIDGESTONE CORPORATION (JP) 2016-02-11 US disclosed