Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499242 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17499440 | 0.86 | TBXA2R (0.40) | ALDH1A1POLBKMT2AMAPTGAA | |
| SCHEMBL17499688 | 0.85 | TBXA2R (0.45) | ALDH1A1POLBKMT2ASMN1; SMN2HPGD | |
| SCHEMBL17499239 | 0.85 | RAB9A (0.46) | ALDH1A1KMT2ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL17499671 | 0.84 | TBXA2R (0.39) | ALDH1A1POLBKMT2ASMN1; SMN2HPGD | |
| SCHEMBL17499124 | 0.84 | GAA (0.37) | ALDH1A1POLBKMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL16098463 | 0.84 | ALDH1A1 (0.56) | ALDH1A1POLBKMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL17499174 | 0.83 | TBXA2R (0.45) | POLBKMT2ASMN1; SMN2CYP1A2MAPT | |
| SCHEMBL16097932 | 0.81 | ALDH1A1 (0.44) | ALDH1A1POLBKMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL17499291 | 0.81 | RAB9A (0.36) | ALDH1A1POLBKMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |