SCHEMBL17499124

SCHEMBL17499124

CC(=Nc1ccccc1O[SiH](C)C)c1ccncc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 7/20 0.37
MAPT P10636 5/20 0.37
KDM4E B2RXH2 2/20 0.37
MTOR P42345 1/20 0.36
ALDH1A1 P00352 5/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KMT2A Q03164 4/20 0.35
MEN1 O00255 3/20 0.35
RAB9A P51151 3/20 0.35
NPC1 O15118 2/20 0.35
POLB P06746 1/20 0.35
CYP3A4 P08684 2/20 0.35
CYP1A2 P05177 2/20 0.33
CYP2D6 P10635 2/20 0.33
LMNA P02545 2/20 0.33
GFER P55789 2/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CYP1A1 P04798 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17499710 0.85 PKM (0.43) GAAMAPTALDH1A1KMT2AMEN1
SCHEMBL17499787 0.84 ALDH1A1 (0.33) MAPTALDH1A1RAB9ALMNAHSD17B10
SCHEMBL17499237 0.84 ALDH1A1 (0.43) GAAMAPTALDH1A1KMT2AMEN1
SCHEMBL15137199 0.83 ALDH1A1 (0.47) GAAMAPTKDM4EALDH1A1RAB9A
SCHEMBL15137200 0.83 ALDH1A1 (0.47) GAAMAPTKDM4EALDH1A1RAB9A
SCHEMBL17499504 0.82 HKDC1 (0.34) MAPTKDM4EALDH1A1RAB9ALMNA
SCHEMBL17499527 0.81 KDM4E (0.37) GAAMAPTKDM4EALDH1A1L3MBTL1
SCHEMBL17499513 0.81 GAA (0.38) GAAMAPTKDM4EMTORALDH1A1
SCHEMBL17499327 0.80 ALDH1A1 (0.32) MAPTALDH1A1LMNAHSD17B10
SCHEMBL17499126 0.79 KDM4E (0.50) GAAMAPTKDM4EALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2969593-B1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES BRIDGESTONE CORP (JP) 2020-11-04 EP disclosed
US-9850328-B2 Polymers functionalized with heterocyclic imines BRIDGESTONE CORPORATION (JP) 2017-12-26 US disclosed
US-20160039958-A1 Polymers Functionalized With Heterocyclic Imines BRIDGESTONE CORPORATION (JP) 2016-02-11 US disclosed