SCHEMBL17499285

SCHEMBL17499285

Cn1cc(CC=Nc2ccccc2O[SiH](C)C)cn1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.35
GABRA5 P31644 1/20 0.35
KDM1A O60341 1/20 0.31
PDE1A P54750 1/20 0.31
PDE1B Q01064 1/20 0.31
PDE1C Q14123 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17499775 0.86 PDE1A (0.38) PDE1APDE1BPDE1CKDM4E
SCHEMBL16102408 0.85 HPGD (0.31)
SCHEMBL16101151 0.85 HPGD (0.31)
SCHEMBL17499429 0.84 KDM1A (0.34) GABRA1GABRA5KDM1APDE1APDE1B
SCHEMBL28039879 0.84 HPGD (0.30)
SCHEMBL28039907 0.84 HPGD (0.30)
SCHEMBL16100969 0.83 GABRA1 (0.32) GABRA1GABRA5
SCHEMBL16101394 0.83 GABRA1 (0.32) GABRA1GABRA5
SCHEMBL28823574 0.82 GABRA1 (0.31) GABRA1GABRA5
SCHEMBL17499110 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2969593-B1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES BRIDGESTONE CORP (JP) 2020-11-04 EP disclosed
US-9850328-B2 Polymers functionalized with heterocyclic imines BRIDGESTONE CORPORATION (JP) 2017-12-26 US disclosed
US-20160039958-A1 Polymers Functionalized With Heterocyclic Imines BRIDGESTONE CORPORATION (JP) 2016-02-11 US disclosed