Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16101394 | 0.99 | GABRA1 (0.32) | GABRA1GABRA5PDE4BJAK2JAK1 | |
| SCHEMBL16102141 | 0.86 | PDE4B (0.39) | PDE4BJAK2JAK1TYK2JAK3 | |
| SCHEMBL16100696 | 0.84 | KDM4E (0.32) | PDE4BJAK2JAK1TYK2JAK3 | |
| SCHEMBL16100969 | 0.83 | GABRA1 (0.32) | GABRA1GABRA5JAK2JAK1TYK2 | |
| SCHEMBL17499285 | 0.82 | GABRA1 (0.35) | GABRA1GABRA5 | |
| SCHEMBL28039900 | 0.81 | MET (0.30) | — | |
| SCHEMBL28039907 | 0.79 | HPGD (0.30) | — | |
| SCHEMBL28039879 | 0.79 | HPGD (0.30) | PDE4B | |
| SCHEMBL16101151 | 0.77 | HPGD (0.31) | — | |
| SCHEMBL16102408 | 0.77 | HPGD (0.31) | PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209268-B | Heterocyclic imine functionalized polymers | 株式会社普利司通 | 2018-05-04 | — | — | CN | disclosed |
| CN-105209268-A | Heterocyclic imine functionalized polymers | BRIDGESTONE CORP | 2015-12-30 | — | — | CN | disclosed |