Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499596 | 0.87 | GRIN2D (0.42) | ALDH1A1SMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL16102503 | 0.84 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL17499130 | 0.84 | NPC1 (0.32) | ALDH1A1SMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL17499643 | 0.82 | HTT (0.32) | ALDH1A1SMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL17499214 | 0.80 | ATM (0.39) | ALDH1A1SMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL16102401 | 0.79 | SMN1; SMN2 (0.31) | ALDH1A1SMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL17499807 | 0.78 | NPC1 (0.31) | ALDH1A1SMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL17499412 | 0.78 | SMN1; SMN2 (0.34) | ALDH1A1SMN1; SMN2RAB9ALMNAMAPT | |
| SCHEMBL16098181 | 0.77 | HTT (0.35) | ALDH1A1SMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL17499482 | 0.74 | ALDH1A1 (0.30) | ALDH1A1SMN1; SMN2RAB9ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |