Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DHX9 | Q08211 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.31 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16101774 | 0.86 | ALDH1A1 (0.45) | SMN1; SMN2RAB9ALMNAALDH1A1HPGD | |
| SCHEMBL17499227 | 0.85 | MAPT (0.32) | LMNAALDH1A1HPGDMAPTDHX9 | |
| SCHEMBL16100347 | 0.85 | GAA (0.34) | SMN1; SMN2RAB9ALMNAHPGD | |
| SCHEMBL17499565 | 0.84 | LRRK2 (0.33) | SMN1; SMN2LMNAALDH1A1MAPTDHX9 | |
| SCHEMBL17499295 | 0.83 | SMN1; SMN2 (0.34) | SMN1; SMN2RAB9ALMNAALDH1A1HPGD | |
| SCHEMBL17499588 | 0.81 | DHX9 (0.33) | SMN1; SMN2RAB9AMAPTDHX9PROKR1 | |
| SCHEMBL17499749 | 0.81 | DHX9 (0.33) | SMN1; SMN2RAB9AMAPTDHX9PROKR1 | |
| SCHEMBL17499294 | 0.78 | ALDH1A1 (0.33) | SMN1; SMN2RAB9ALMNAALDH1A1HPGD | |
| SCHEMBL17499615 | 0.78 | ALDH1A1 (0.33) | SMN1; SMN2RAB9ALMNAALDH1A1MAPT | |
| SCHEMBL17499513 | 0.76 | GAA (0.38) | SMN1; SMN2RAB9ALMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |