Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 10/20 | 0.40 |
| ▸ | NPC1 | O15118 | 7/20 | 0.39 |
| ▸ | PKM | P14618 | 4/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499319 | 0.90 | KDM4E (0.44) | KDM4EHSP90AA1HKDC1MAPTALDH1A1 | |
| SCHEMBL17499160 | 0.87 | KMT2A (0.37) | KDM4EHSP90AA1HKDC1MAPTALDH1A1 | |
| SCHEMBL17499442 | 0.85 | LMNA (0.40) | KDM4EMAPTALDH1A1NFKB1NFKB2 | |
| SCHEMBL17499172 | 0.85 | RAB9A (0.50) | KDM4EHSP90AA1HKDC1MAPTALDH1A1 | |
| SCHEMBL17499126 | 0.85 | KDM4E (0.50) | KDM4EHKDC1MAPTALDH1A1LMNA | |
| SCHEMBL17499518 | 0.85 | GAA (0.38) | KDM4EMAPTALDH1A1LMNARAB9A | |
| SCHEMBL28039914 | 0.84 | GAA (0.37) | KDM4EMAPTALDH1A1LMNARAB9A | |
| SCHEMBL22607507 | 0.83 | KDM4E (0.45) | KDM4EHSP90AA1HKDC1MAPTALDH1A1 | |
| SCHEMBL17499188 | 0.83 | KDM4E (0.45) | KDM4EHSP90AA1HKDC1MAPTALDH1A1 | |
| SCHEMBL17499219 | 0.82 | HKDC1 (0.36) | KDM4EHSP90AA1HKDC1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |