Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | FGB | P02675 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.39 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499358 | 1.00 | ALDH1A1 (0.45) | ALDH1A1KDM4EHSD17B10CASP1RXFP1 | |
| SCHEMBL17499135 | 0.86 | KDM4E (0.33) | ALDH1A1KDM4EHSD17B10CASP1RXFP1 | |
| SCHEMBL17499131 | 0.86 | KDM4E (0.33) | ALDH1A1KDM4EHSD17B10CASP1RXFP1 | |
| SCHEMBL14769327 | 0.81 | MAPT (0.41) | ALDH1A1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL17499767 | 0.77 | GRIN2B (0.40) | ALDH1A1HSD17B10CASP1MEN1KMT2A | |
| SCHEMBL16101288 | 0.77 | MEN1 (0.39) | ALDH1A1KDM4EHSD17B10CASP1RXFP1 | |
| SCHEMBL17499111 | 0.77 | TDP1 (0.38) | ALDH1A1KDM4EHSD17B10CASP1MEN1 | |
| SCHEMBL17499764 | 0.77 | GRIN2B (0.40) | ALDH1A1HSD17B10CASP1MEN1KMT2A | |
| SCHEMBL16097348 | 0.75 | ALDH1A1 (0.45) | ALDH1A1KDM4EHSD17B10CASP1RXFP1 | |
| SCHEMBL16097350 | 0.75 | ALDH1A1 (0.45) | ALDH1A1KDM4EHSD17B10CASP1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-9545623-B2 | Nickel-based catalytic composition and method of oligomerization of olefins using said composition | IFP Energies Nouvelles (FR) | 2017-01-17 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |