Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499356 | 0.81 | ALDH1A1 (0.45) | MAPTALDH1A1SMN1; SMN2NPC1KDM4E | |
| SCHEMBL17499358 | 0.81 | ALDH1A1 (0.45) | MAPTALDH1A1SMN1; SMN2NPC1KDM4E | |
| SCHEMBL17499131 | 0.79 | KDM4E (0.33) | ALDH1A1KDM4EHTTNPSR1GAA | |
| SCHEMBL17499135 | 0.79 | KDM4E (0.33) | ALDH1A1KDM4EHTTNPSR1GAA | |
| SCHEMBL1254916 | 0.72 | LPO (0.43) | ALDH1A1KDM4EHTTHPGDKMT2A | |
| SCHEMBL2380580 | 0.71 | KCNJ1 (0.34) | MAPTALDH1A1KDM4ERECQLPOLB | |
| SCHEMBL2380573 | 0.71 | KCNJ1 (0.34) | MAPTALDH1A1KDM4ERECQLPOLB | |
| SCHEMBL18855886 | 0.71 | PTP4A3 (0.33) | — | |
| SCHEMBL814014 | 0.71 | KDM4E (0.60) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4256486 | 0.71 | LPO (0.39) | ALDH1A1HTTHPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9545623-B2 | Nickel-based catalytic composition and method of oligomerization of olefins using said composition | IFP Energies Nouvelles (FR) | 2017-01-17 | — | — | US | disclosed |
| US-20130066128-A1 | NOVEL NICKEL-BASED CATALYTIC COMPOSITION AND METHOD OF OLIGOMERIZATION OF OLEFINS USING SAID COMPOSITION | IFP Energies Nouvelles (FR) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130066128-A1 | NOVEL NICKEL-BASED CATALYTIC COMPOSITION AND METHOD OF OLIGOMERIZATION OF OLEFINS USING SAID COMPOSITION | POR, NIT2, NOD2 | MAPT 2682/4885ALDH1A1 3008/4885SMN1; SMN2 3712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.