SCHEMBL17499362

SCHEMBL17499362

Cc1ccc(O[SiH](C)C)c(N=C(c2ccccc2)c2cnccn2)c1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TBXA2R P21731 3/20 0.41
TBXAS1 P24557 3/20 0.41
ALDH1A1 P00352 6/20 0.37
KMT2A Q03164 4/20 0.37
MAPT P10636 3/20 0.37
MEN1 O00255 1/20 0.37
GAA P10253 1/20 0.35
POLB P06746 1/20 0.35
TSHR P16473 1/20 0.35
KDM4E B2RXH2 1/20 0.35
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28040288 0.99 TBXA2R (0.40) TBXA2RTBXAS1ALDH1A1KMT2AMAPT
SCHEMBL17499277 0.91 TBXA2R (0.43) TBXA2RTBXAS1ALDH1A1KMT2AMAPT
SCHEMBL28040334 0.90 TBXA2R (0.43) TBXA2RTBXAS1ALDH1A1KMT2AMAPT
SCHEMBL17499442 0.89 LMNA (0.40) ALDH1A1KMT2AMAPTMEN1GAA
SCHEMBL16098733 0.87 KDM4E (0.44) TBXA2RTBXAS1ALDH1A1KMT2AMAPT
SCHEMBL17499174 0.87 TBXA2R (0.45) TBXA2RTBXAS1KMT2AMAPTMEN1
SCHEMBL16095522 0.85 TBXA2R (0.42) TBXA2RTBXAS1ALDH1A1KMT2AMAPT
SCHEMBL17499518 0.84 GAA (0.38) ALDH1A1KMT2AMAPTMEN1GAA
SCHEMBL17499181 0.84 TBXA2R (0.35) TBXA2RALDH1A1KMT2AMAPTMEN1
SCHEMBL28039914 0.83 GAA (0.37) ALDH1A1KMT2AMAPTMEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2969593-B1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES BRIDGESTONE CORP (JP) 2020-11-04 EP disclosed
US-9850328-B2 Polymers functionalized with heterocyclic imines BRIDGESTONE CORPORATION (JP) 2017-12-26 US disclosed
US-20160039958-A1 Polymers Functionalized With Heterocyclic Imines BRIDGESTONE CORPORATION (JP) 2016-02-11 US disclosed