SCHEMBL28040288

SCHEMBL28040288

Cc1ccc(O[SiH](C)C)c(N=C(c2ccccc2)c2cnccn2)c1.[H+]

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TBXA2R P21731 4/20 0.40
TBXAS1 P24557 4/20 0.40
ALDH1A1 P00352 5/20 0.36
MAPT P10636 3/20 0.36
KMT2A Q03164 3/20 0.36
MEN1 O00255 1/20 0.36
GAA P10253 1/20 0.35
POLB P06746 1/20 0.34
TSHR P16473 1/20 0.34
KDM4E B2RXH2 1/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17499362 0.99 TBXA2R (0.41) TBXA2RTBXAS1ALDH1A1MAPTKMT2A
SCHEMBL28040334 0.91 TBXA2R (0.43) TBXA2RTBXAS1ALDH1A1MAPTKMT2A
SCHEMBL17499277 0.90 TBXA2R (0.43) TBXA2RTBXAS1ALDH1A1MAPTKMT2A
SCHEMBL17499442 0.88 LMNA (0.40) ALDH1A1MAPTKMT2AMEN1GAA
SCHEMBL16098733 0.86 KDM4E (0.44) TBXA2RTBXAS1ALDH1A1MAPTKMT2A
SCHEMBL17499174 0.86 TBXA2R (0.45) TBXA2RTBXAS1MAPTKMT2AMEN1
SCHEMBL16095522 0.84 TBXA2R (0.42) TBXA2RTBXAS1ALDH1A1MAPTKMT2A
SCHEMBL28039914 0.84 GAA (0.37) ALDH1A1MAPTKMT2AMEN1GAA
SCHEMBL17499518 0.83 GAA (0.38) ALDH1A1MAPTKMT2AMEN1GAA
SCHEMBL17499181 0.83 TBXA2R (0.35) TBXA2RALDH1A1MAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105209268-B Heterocyclic imine functionalized polymers 株式会社普利司通 2018-05-04 CN disclosed
CN-105209268-A Heterocyclic imine functionalized polymers BRIDGESTONE CORP 2015-12-30 CN disclosed