Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SRC | P12931 | 2/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499521 | 0.90 | TBXA2R (0.38) | TBXA2RALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL17499442 | 0.88 | LMNA (0.40) | ALDH1A1HTTSMN1; SMN2KMT2AMAPT | |
| SCHEMBL16095818 | 0.86 | HTT (0.46) | TBXA2RALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL17499671 | 0.86 | TBXA2R (0.39) | TBXA2RALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL16099287 | 0.84 | MAPT (0.37) | TBXA2RALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL17499362 | 0.84 | TBXA2R (0.41) | TBXA2RALDH1A1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL28040288 | 0.83 | TBXA2R (0.40) | TBXA2RALDH1A1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL17499160 | 0.82 | KMT2A (0.37) | ALDH1A1HTTSMN1; SMN2KMT2AMAPT | |
| SCHEMBL16104946 | 0.81 | ALDH1A1 (0.34) | TBXA2RALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL17499782 | 0.80 | ESR1 (0.33) | ALDH1A1HTTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |