Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28039871 | 0.99 | NOTUM (0.32) | NOTUMGABRA1GABRA5TRPM5 | |
| SCHEMBL16098341 | 0.87 | SYK (0.37) | NOTUMTRPM5MEN1KMT2A | |
| SCHEMBL17499574 | 0.86 | SYK (0.38) | GABRA1GABRA5 | |
| SCHEMBL16097834 | 0.85 | NOTUM (0.33) | NOTUMGABRA1GABRA5TRPM5NAAA | |
| SCHEMBL17499680 | 0.82 | SCN8A (0.32) | NOTUM | |
| SCHEMBL17499266 | 0.82 | GABRA1 (0.32) | NOTUMGABRA1GABRA5MEN1KMT2A | |
| SCHEMBL16096440 | 0.82 | KDM4E (0.32) | — | |
| SCHEMBL17499104 | 0.80 | CTH (0.33) | NOTUMMEN1KMT2A | |
| SCHEMBL16101727 | 0.79 | CYP2C9 (0.32) | — | |
| SCHEMBL28040290 | 0.79 | KDM4E (0.33) | NOTUMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |