Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499441 | 0.99 | NOTUM (0.33) | NOTUMTRPM5GABRA1GABRA5 | |
| SCHEMBL16098341 | 0.86 | SYK (0.37) | NOTUMTRPM5 | |
| SCHEMBL17499574 | 0.85 | SYK (0.38) | GABRA1GABRA5 | |
| SCHEMBL16097834 | 0.84 | NOTUM (0.33) | NOTUMTRPM5GABRA1GABRA5 | |
| SCHEMBL17499680 | 0.81 | SCN8A (0.32) | NOTUM | |
| SCHEMBL17499266 | 0.81 | GABRA1 (0.32) | NOTUMGABRA1GABRA5 | |
| SCHEMBL16096440 | 0.81 | KDM4E (0.32) | — | |
| SCHEMBL28040290 | 0.80 | KDM4E (0.33) | NOTUM | |
| SCHEMBL17499104 | 0.79 | CTH (0.33) | NOTUM | |
| SCHEMBL16101727 | 0.78 | CYP2C9 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209268-A | Heterocyclic imine functionalized polymers | BRIDGESTONE CORP | 2015-12-30 | — | — | CN | disclosed |