SCHEMBL17499604

SCHEMBL17499604

Cc1cccc(O[Si](C)(C)C)c1N=C(c1ccccc1)c1cnn(C)c1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FYN P06241 2/20 0.32
PROKR1 Q8TCW9 1/20 0.32
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
LMNA P02545 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16096302 0.88 EGLN1 (0.36) FYNRAB9ASMN1; SMN2
SCHEMBL17499616 0.85 FYN (0.32) FYNRAB9ASMN1; SMN2
SCHEMBL17499749 0.85 DHX9 (0.33) PROKR1RAB9ASMN1; SMN2
SCHEMBL28039912 0.84 FYN (0.31) FYNRAB9ASMN1; SMN2
SCHEMBL16100347 0.83 GAA (0.34) FYNRAB9ASMN1; SMN2LMNAHPGD
SCHEMBL16101494 0.82 ESR2 (0.37) FYNPROKR1RAB9ASMN1; SMN2LMNA
SCHEMBL16102013 0.80 PTGDR2 (0.32) FYNPROKR1RAB9ASMN1; SMN2LMNA
SCHEMBL16102710 0.80 LMNA (0.31) SMN1; SMN2LMNAHPGD
SCHEMBL16105009 0.79 PTGDR2 (0.34) RAB9ASMN1; SMN2HPGD
SCHEMBL16095840 0.77 TBXA2R (0.36) RAB9ASMN1; SMN2LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2969593-B1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES BRIDGESTONE CORP (JP) 2020-11-04 EP disclosed
US-9850328-B2 Polymers functionalized with heterocyclic imines BRIDGESTONE CORPORATION (JP) 2017-12-26 US disclosed
US-20160039958-A1 Polymers Functionalized With Heterocyclic Imines BRIDGESTONE CORPORATION (JP) 2016-02-11 US disclosed