Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16102013 | 0.88 | PTGDR2 (0.32) | SMN1; SMN2RAB9AFYNLMNAHPGD | |
| SCHEMBL16105009 | 0.87 | PTGDR2 (0.34) | SMN1; SMN2RAB9AHPGD | |
| SCHEMBL16102524 | 0.87 | NOS3 (0.38) | GAASMN1; SMN2RAB9ALMNA | |
| SCHEMBL17499412 | 0.85 | SMN1; SMN2 (0.34) | SMN1; SMN2RAB9ALMNAHPGD | |
| SCHEMBL17499566 | 0.84 | GAA (0.33) | GAASMN1; SMN2RAB9AFYNLMNA | |
| SCHEMBL17499604 | 0.83 | FYN (0.32) | SMN1; SMN2RAB9AFYNLMNAHPGD | |
| SCHEMBL16101494 | 0.83 | ESR2 (0.37) | GAASMN1; SMN2RAB9AFYNLMNA | |
| SCHEMBL16102283 | 0.80 | ALDH1A1 (0.35) | SMN1; SMN2FYNHPGD | |
| SCHEMBL16097113 | 0.79 | TBXA2R (0.40) | GAAESR1ESR2 | |
| SCHEMBL16097932 | 0.79 | ALDH1A1 (0.44) | GAASMN1; SMN2RAB9AHPGDESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |
| EP-2969593-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | Bridgestone Corporation (JP) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014149931-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORPORATION (JP) | 2014-09-25 | — | — | WO | disclosed |