Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16102401 | 0.88 | SMN1; SMN2 (0.31) | GRIN2BGRIN1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL28823545 | 0.88 | SIGMAR1 (0.41) | SIGMAR1SMN1; SMN2KCNH2CYP1A2CYP3A4 | |
| SCHEMBL17499432 | 0.87 | NPC1 (0.30) | SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL17499596 | 0.78 | GRIN2D (0.42) | GRIN2BGRIN1SIGMAR1SMN1; SMN2LMNA | |
| SCHEMBL16101407 | 0.75 | GRIN2B (0.41) | GRIN2BGRIN1SIGMAR1SMN1; SMN2LMNA | |
| SCHEMBL17499398 | 0.75 | RAB9A (0.35) | SMN1; SMN2LMNAKDM4EALDH1A1TDP1 | |
| SCHEMBL17499814 | 0.74 | GRIN2B (0.44) | GRIN2BGRIN1SMN1; SMN2LMNAMTNR1A | |
| SCHEMBL17499639 | 0.73 | CYP1A2 (0.52) | GRIN2BGRIN1SIGMAR1SMN1; SMN2LMNA | |
| SCHEMBL16096026 | 0.73 | CYP1A2 (0.52) | GRIN2BGRIN1SIGMAR1SMN1; SMN2LMNA | |
| SCHEMBL17499731 | 0.72 | GRIN2B (0.42) | GRIN2BGRIN1SMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |
| CN-105209268-A | Heterocyclic imine functionalized polymers | BRIDGESTONE CORP | 2015-12-30 | — | — | CN | disclosed |