Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | MGAM | O43451 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CCND3 | P30281 | 1/20 | 0.54 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1343443 | 0.80 | CNR2 (0.78) | CNR2MAPTMGAMKDM4EHDAC8 | |
| SCHEMBL11173812 | 0.78 | CNR2 (0.55) | CNR2MAPTMGAMKDM4EHDAC8 | |
| SCHEMBL30227109 | 0.78 | CNR2 (1.00) | CNR2MAPTMGAMKDM4EHDAC8 | |
| SCHEMBL7832199 | 0.78 | CNR2 (1.00) | CNR2MAPTMGAMKDM4EHDAC8 | |
| SCHEMBL11173816 | 0.76 | KDM4E (0.60) | CNR2MAPTMGAMKDM4EHDAC8 | |
| SCHEMBL6424145 | 0.75 | P2RX7 (0.47) | MAPTKDM4ECCND3CDK6RAB9A | |
| SCHEMBL9576590 | 0.73 | CNR2 (0.53) | CNR2MAPTMGAMKDM4EHDAC8 | |
| SCHEMBL30227014 | 0.72 | CNR2 (0.75) | CNR2MAPTMGAMKDM4EHDAC8 | |
| SCHEMBL11180845 | 0.72 | CNR2 (1.00) | CNR2MAPTMGAMKDM4EHDAC8 | |
| SCHEMBL371069 | 0.72 | TSHR (0.54) | KDM4ECCND3CDK6GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3177621-B1 | NOVEL HDAC6 INHIBITORS AND THEIR USES | UNIV REGENSBURG (DE) | 2021-11-10 | — | — | EP | disclosed |
| US-10106540-B2 | HDAC6 inhibitors and their uses | UNIVERSITÄT REGENSBURG (DE) | 2018-10-23 | — | — | US | disclosed |
| US-20170210743-A1 | NOVEL HDAC6 INHIBITORS AND THEIR USES | Universitätsklinikum Jena (DE) | 2017-07-27 | — | — | US | disclosed |
| EP-3177621-A1 | NOVEL HDAC6 INHIBITORS AND THEIR USES | Universität Regensburg (DE) | 2017-06-14 | — | — | EP | disclosed |
| WO-2016020369-A1 | NOVEL HDAC6 INHIBITORS AND THEIR USES | UNIVERSITÄT REGENSBURG (DE) | 2016-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170210743-A1 | NOVEL HDAC6 INHIBITORS AND THEIR USES | HDAC6, HDAC5, HDAC4 | CNR2 4422/4885MAPT 1414/4885MGAM 2540/4885 |
| US-10106540-B2 | HDAC6 inhibitors and their uses | HDAC6, HDAC5, HDAC4 | CNR2 4483/4885MAPT 1324/4885MGAM 2155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.