Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 6/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1750074 | 1.00 | MAOA (0.42) | MAOAMAOBCYP1A2HTR2ADRD2 | |
| SCHEMBL8912020 | 0.82 | TSHR (0.43) | MAOAMAOBCYP1A2HTR2ADRD2 | |
| SCHEMBL1751341 | 0.82 | TSHR (0.43) | MAOAMAOBCYP1A2HTR2ADRD2 | |
| SCHEMBL11095966 | 0.82 | TSHR (0.43) | MAOAMAOBCYP1A2HTR2ADRD2 | |
| SCHEMBL599812 | 0.79 | CYP1A2 (0.44) | MAOAMAOBCYP1A2KDM4EALDH1A1 | |
| SCHEMBL1750029 | 0.78 | CES1 (0.50) | MAOAMAOBCYP1A2CYP3A4KDM4E | |
| SCHEMBL2797054 | 0.78 | HTR2A (0.38) | MAOAMAOBHTR2A | |
| SCHEMBL205284 | 0.73 | — | — | |
| SCHEMBL8776016 | 0.73 | CYP2A6 (0.36) | TSHRCYP3A4ALOX15HSD17B10KDM4E | |
| SCHEMBL22081972 | 0.73 | CYP1A2 (0.62) | MAOAMAOBCYP1A2HTR2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494080-B1 | Azine-based dimeric charge transport materials | SAMSUNG ELECTRONICS CO LTD (KR) | 2008-04-02 | — | — | EP | claimed |
| US-7115347-B2 | Azine-based dimeric charge transport materials | SAMSUNG ELECTRONICS CO., LTD (CN) | 2006-10-03 | — | — | US | claimed |
| EP-1494080-A1 | Azine-based dimeric charge transport materials | Samsung Electronics Co., Ltd. (KR) | 2005-01-05 | — | — | EP | claimed |
| US-20040265717-A1 | Azine-based dimeric charge transport materials | S-PRINTING SOLUTION CO., LTD. (KR) | 2004-12-30 | — | — | US | claimed |
| US-7968539-B2 | reversed chloroquines; to treat chloroquine resistant/sensitive malaria parasites; N'-(7-Chloro-quinolin-4-yl)-N-[3-(10,11-dihydro-dibenzo[b,f]azepin-5-yl)-propyl]-N-methyl-propane-1,3-diamine | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND STATE UNIVERSITY (US) | 2011-06-28 | — | — | US | disclosed |
| US-20080188462-A1 | Quinoline Derivatives And Uses Thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-08-07 | — | — | US | disclosed |
| EP-1494080-B1 | Azine-based dimeric charge transport materials | SAMSUNG ELECTRONICS CO LTD (KR) | 2008-04-02 | — | — | EP | disclosed |
| US-7115347-B2 | Azine-based dimeric charge transport materials | SAMSUNG ELECTRONICS CO., LTD (CN) | 2006-10-03 | — | — | US | disclosed |
| EP-1494080-A1 | Azine-based dimeric charge transport materials | Samsung Electronics Co., Ltd. (KR) | 2005-01-05 | — | — | EP | disclosed |
| US-20040265717-A1 | Azine-based dimeric charge transport materials | S-PRINTING SOLUTION CO., LTD. (KR) | 2004-12-30 | — | — | US | disclosed |
| WO-1989003212-A1 | 3,5-DIHYDROXY-6,8-NONADIENOIC ACIDS AND DERIVATIVES AS HYPOCHOLESTEROLEMIC AGENTS | PFIZER INC. (US) | 1989-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188462-A1 | Quinoline Derivatives And Uses Thereof | RECQL, QARS1, QTRT1 | MAOA 2917/4885MAOB 2445/4885CYP1A2 446/4885 |
| US-20040265717-A1 | Azine-based dimeric charge transport materials | SLC1A2, SLC35E1, SLC43A1 | MAOA 743/4885MAOB 541/4885CYP1A2 2087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.