Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 8/20 | 0.64 |
| ▸ | PDE2A | O00408 | 1/20 | 0.49 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.46 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.46 |
| ▸ | PI4KA | P42356 | 1/20 | 0.46 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.46 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10749310 | 1.00 | AHCY (0.64) | AHCYPDE2AHSPA5ADORA1NT5E | |
| SCHEMBL10749299 | 1.00 | AHCY (0.64) | AHCYPDE2AHSPA5ADORA1NT5E | |
| SCHEMBL9025101 | 0.84 | AHCY (0.53) | AHCYPDE2AHSPA5ADORA1NT5E | |
| SCHEMBL9025109 | 0.84 | AHCY (0.53) | AHCYPDE2AHSPA5ADORA1NT5E | |
| SCHEMBL10747082 | 0.84 | AHCY (0.49) | AHCYPDE2AHSPA5ADORA1NT5E | |
| SCHEMBL17501769 | 0.84 | AHCY (0.49) | AHCYPDE2AHSPA5ADORA1NT5E | |
| SCHEMBL17501760 | 0.84 | AHCY (0.47) | AHCYPDE2AHSPA5ADORA1PI4KA | |
| SCHEMBL17501729 | 0.84 | AHCY (0.47) | AHCYPDE2AHSPA5ADORA1DOT1L | |
| SCHEMBL10431915 | 0.82 | AHCY (0.62) | AHCYPDE2AHSPA5ADORA1NT5E | |
| SCHEMBL8781156 | 0.81 | AHCY (0.55) | AHCYNT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10787478-B2 | Enantiomers of the 1′,6′-isomer of neplanocin A | AUBURN UNIVERSITY (US) | 2020-09-29 | — | — | US | disclosed |
| US-20190202854-A1 | ENANTIOMERS OF THE 1',6'-ISOMER OF NEPLANOCIN A | AUBURN UNIVERSITY | 2019-07-04 | — | — | US | disclosed |
| US-10227373-B2 | Enantiomers of the 1′,6′-isomer of neplanocin A | AUBURN UNIVERSITY (US) | 2019-03-12 | — | — | US | disclosed |
| US-20170260223-A1 | ENANTIOMERS OF THE 1',6'-ISOMER OF NEPLANOCIN A | AUBURN UNIVERSITY | 2017-09-14 | — | — | US | disclosed |
| EP-3177296-A1 | ENANTIOMERS OF THE 1',6'-ISOMER OF NEPLANOCIN A | Auburn University (US) | 2017-06-14 | — | — | EP | disclosed |
| US-9657048-B2 | Enantiomers of the 1′,6′-isomer of neplanocin A | AUBURN UNIVERSITY (US) | 2017-05-23 | — | — | US | disclosed |
| WO-2016022563-A1 | ENANTIOMERS OF THE 1',6'-ISOMER OF NEPLANOCIN A | AUBURN UNIVERSITY (US) | 2016-02-11 | — | — | WO | disclosed |
| US-20160039860-A1 | ENANTIOMERS OF THE 1',6'-ISOMER OF NEPLANOCIN A | AUBURN UNIVERSITY | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10787478-B2 | Enantiomers of the 1′,6′-isomer of neplanocin A | NME2, NTPCR, SAMHD1 | AHCY 32/4885PDE2A 1593/4885HSPA5 2790/4885 |
| US-10227373-B2 | Enantiomers of the 1′,6′-isomer of neplanocin A | NME2, NTPCR, SAMHD1 | AHCY 32/4885PDE2A 1593/4885HSPA5 2790/4885 |
| US-20170260223-A1 | ENANTIOMERS OF THE 1',6'-ISOMER OF NEPLANOCIN A | NME2, NTPCR, SAMHD1 | AHCY 32/4885PDE2A 1573/4885HSPA5 2775/4885 |
| US-20160039860-A1 | ENANTIOMERS OF THE 1',6'-ISOMER OF NEPLANOCIN A | NME2, NTPCR, SAMHD1 | AHCY 32/4885PDE2A 1573/4885HSPA5 2775/4885 |
| US-20190202854-A1 | ENANTIOMERS OF THE 1',6'-ISOMER OF NEPLANOCIN A | NME2, NTPCR, SAMHD1 | AHCY 32/4885PDE2A 1573/4885HSPA5 2775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.