Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL283987 | 0.82 | ALDH1A1 (0.38) | — | |
| SCHEMBL17502571 | 0.78 | L3MBTL1 (0.32) | — | |
| SCHEMBL17502583 | 0.78 | RAPGEF4 (0.31) | — | |
| SCHEMBL6099464 | 0.74 | POLB (0.40) | — | |
| SCHEMBL16078015 | 0.71 | ALDH1A1 (0.37) | P2RX7 | |
| SCHEMBL18122718 | 0.67 | HTT (0.45) | P2RX7 | |
| SCHEMBL22430556 | 0.63 | HSD17B10 (0.50) | P2RX7 | |
| SCHEMBL16482032 | 0.62 | HCRTR1 (0.32) | P2RX7 | |
| SCHEMBL22430483 | 0.62 | HSD17B10 (0.45) | P2RX7 | |
| SCHEMBL13550041 | 0.61 | RAPGEF4 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016022965-A1 | PERSISTENT CARBENE ADDUCTS AND RELATED METHODS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-02-11 | — | — | WO | disclosed |