Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1032674 | 1.00 | FBP1 (0.47) | FBP1MEN1JAK2MITFALDH1A1 | |
| SCHEMBL13092439 | 0.85 | ESR1 (0.50) | FBP1MEN1JAK2MITFALDH1A1 | |
| SCHEMBL6466356 | 0.84 | FBP1 (0.59) | FBP1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL11468825 | 0.84 | FBP1 (0.61) | FBP1MEN1JAK2MITFALDH1A1 | |
| SCHEMBL11468826 | 0.84 | FBP1 (0.61) | FBP1MEN1JAK2MITFALDH1A1 | |
| SCHEMBL6466353 | 0.84 | FBP1 (0.59) | FBP1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL6466349 | 0.84 | FBP1 (0.59) | FBP1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL23112863 | 0.83 | FBP1 (0.61) | FBP1MEN1JAK2MITFALDH1A1 | |
| SCHEMBL8137951 | 0.83 | FBP1 (0.61) | FBP1MEN1JAK2MITFALDH1A1 | |
| SCHEMBL11003556 | 0.81 | FBP1 (0.51) | FBP1MEN1JAK2MITFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968591-B2 | 1,3-disubstituted 4-methyl-1H-pyrrole-2-carboxamides and their use in medicaments | GRUENENTHAL GMBH (DE) | 2011-06-28 | — | — | US | disclosed |
| US-20090137573-A1 | 1,3-Disubstituted 4-methyl-1H-pyrrole-2-carboxamides and their Use in Medicaments | GRUENENTHAL GMBH (DE) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137573-A1 | 1,3-Disubstituted 4-methyl-1H-pyrrole-2-carboxamides and their Use in Medicaments | OPRL1, TPH1, OPRK1 | FBP1 603/4885MEN1 4776/4885JAK2 2418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.