Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17505172 | 0.77 | KMT2A (0.41) | ALDH1A1SMN1; SMN2MAPTKDM4EHSD17B10 | |
| SCHEMBL17505148 | 0.77 | GRIA1 (0.53) | ALDH1A1MAPTRECQLKDM4EHPGD | |
| SCHEMBL17505178 | 0.73 | KDM4E (0.61) | ALDH1A1SMN1; SMN2KDM4EHSD17B10HPGD | |
| SCHEMBL28205755 | 0.72 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPTRECQLKDM4E | |
| SCHEMBL3684194 | 0.71 | GRIN2D (0.61) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL7276588 | 0.71 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL12501407 | 0.69 | NPC1 (0.48) | ALDH1A1SMN1; SMN2MAPTKDM4EHSD17B10 | |
| SCHEMBL11575967 | 0.69 | GPR35 (0.57) | ALDH1A1SMN1; SMN2MAPTRECQLKDM4E | |
| SCHEMBL12501374 | 0.69 | APEX1 (0.51) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL14651329 | 0.69 | KMT2A (0.47) | ALDH1A1HPGDKMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016022915-A1 | 6-SULFONYLAMINO QUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | THE REGENT OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-02-11 | — | — | WO | disclosed |