Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 6/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 6/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 6/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 6/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CTSV | O60911 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17505164 | 0.79 | AR (0.47) | MAPTALDH1A1CTSVCTSLKDM4E | |
| SCHEMBL17505208 | 0.76 | KDM4E (0.41) | MAPTHTTGRIN2DGRIN3BGRIN1 | |
| SCHEMBL17505168 | 0.72 | ALDH1A1 (0.44) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL17505161 | 0.72 | AR (0.43) | MAPTPARP1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL17505194 | 0.69 | GRIN2D (0.38) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL15190610 | 0.69 | ATM (0.53) | MAPTSMN1; SMN2KDM4E | |
| SCHEMBL29626851 | 0.69 | ATM (0.53) | MAPTSMN1; SMN2KDM4E | |
| SCHEMBL17505149 | 0.67 | POLB (0.45) | MAPT | |
| SCHEMBL7051536 | 0.66 | KCNJ1 (0.54) | MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL23674207 | 0.66 | MAPT (0.40) | MAPTHTTALDH1A1CTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016022915-A1 | 6-SULFONYLAMINO QUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | THE REGENT OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-02-11 | — | — | WO | disclosed |