Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17505194 | 0.81 | GRIN2D (0.38) | KDM4EALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL17505164 | 0.78 | AR (0.47) | KDM4EALDH1A1NPSR1HTR1AHTR2C | |
| SCHEMBL17505149 | 0.77 | POLB (0.45) | HTR1AMAPTPOLB | |
| SCHEMBL17505144 | 0.76 | MAPT (0.36) | KDM4EALDH1A1HTTGRIN2DGRIN3B | |
| SCHEMBL15190610 | 0.76 | ATM (0.53) | KDM4EMAPTPOLB | |
| SCHEMBL29626851 | 0.76 | ATM (0.53) | KDM4EMAPTPOLB | |
| SCHEMBL31444686 | 0.75 | GRIA1 (0.55) | HTTMAPTPOLB | |
| SCHEMBL7063585 | 0.73 | KDM4E (0.58) | KDM4EALDH1A1HTTMAPTHPGD | |
| SCHEMBL15690453 | 0.68 | FLT3 (0.51) | KDM4EALDH1A1PDE10AGRIN2DGRIN3B | |
| SCHEMBL7051536 | 0.68 | KCNJ1 (0.54) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016022915-A1 | 6-SULFONYLAMINO QUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | THE REGENT OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-02-11 | — | — | WO | disclosed |