Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 8/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 8/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 8/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 8/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 8/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17505208 | 0.81 | KDM4E (0.41) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL17505149 | 0.80 | POLB (0.45) | POLBMAPTPKM | |
| SCHEMBL30372157 | 0.74 | DAO (0.41) | DAOALDH1A1CYP3A4 | |
| SCHEMBL24207597 | 0.73 | GRIA1 (0.60) | DAOGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7063585 | 0.71 | KDM4E (0.58) | ALDH1A1LMNAMAPTHPGDKDM4E | |
| SCHEMBL17505144 | 0.69 | MAPT (0.36) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL27590744 | 0.69 | SMAD3 (0.53) | FFAR1DAOALDH1A1LMNACYP1A2 | |
| SCHEMBL17505168 | 0.68 | ALDH1A1 (0.44) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL17505161 | 0.68 | AR (0.43) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL11551629 | 0.68 | KCNJ1 (0.50) | FFAR1ALDH1A1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016022915-A1 | 6-SULFONYLAMINO QUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | THE REGENT OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-02-11 | — | — | WO | disclosed |