SCHEMBL17505151

SCHEMBL17505151

COCCCc1cc(=O)[nH]c2ccc(N)cc12

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AR P10275 4/20 0.46
PARP1 P09874 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
CA12 O43570 1/20 0.38
CA9 Q16790 1/20 0.38
HPGD P15428 1/20 0.37
CYP2C19 P33261 1/20 0.37
HCAR2 Q8TDS4 1/20 0.37
NGFR P08138 1/20 0.37
MAPKAPK2 P49137 1/20 0.36
RPS6KA3 P51812 1/20 0.36
CSNK2A1 P68400 1/20 0.36
PLK3 Q9H4B4 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
GAA P10253 1/20 0.36
DAO P14920 1/20 0.35
ALDH1A1 P00352 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17505211 0.82 AR (0.49) ARPARP1CA12CA9HPGD
SCHEMBL17505190 0.82 AR (0.49) ARPARP1L3MBTL1CA12CA9
SCHEMBL1770840 0.79 AR (0.55) ARPARP1CA12CA9HPGD
SCHEMBL8369447 0.79 AR (0.51) ARPARP1CA12CA9HPGD
SCHEMBL17505198 0.77 PARP1 (0.44) ARPARP1CA12CA9HPGD
Hydrochloric Acid SCHEMBL8367852 0.77 AR (0.50) ARPARP1CA12CA9HPGD
SCHEMBL13439584 0.75 AR (0.58) ARPARP1CA12CA9HPGD
SCHEMBL12667293 0.73 AR (0.49) ARPARP1MEN1KMT2AGAA
SCHEMBL1771739 0.72 AR (0.56) ARPARP1L3MBTL1CA12CA9
SCHEMBL1420703 0.71 LMNA (0.62) ARPARP1CA12CA9HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016022915-A1 6-SULFONYLAMINO QUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS THE REGENT OF THE UNIVERSITY OF CALIFORNIA (US) 2016-02-11 WO disclosed