Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.51 |
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NGFR | P08138 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8367852 | 0.98 | AR (0.50) | ARPARP1CA12CA9PDE10A | |
| SCHEMBL17505190 | 0.91 | AR (0.49) | ARPARP1CA12CA9PDE10A | |
| SCHEMBL1770840 | 0.82 | AR (0.55) | ARPARP1CA12CA9PDE10A | |
| SCHEMBL17505211 | 0.82 | AR (0.49) | ARPARP1CA12CA9PDE10A | |
| SCHEMBL9766056 | 0.81 | ALDH1A1 (0.46) | ARCA12CA9HPGDCYP2C19 | |
| SCHEMBL13439584 | 0.81 | AR (0.58) | ARPARP1CA12CA9PDE10A | |
| SCHEMBL8368811 | 0.79 | ALDH1A1 (0.56) | HPGDCYP2C19TNKS2MITF | |
| SCHEMBL17505151 | 0.79 | AR (0.46) | ARPARP1CA12CA9HPGD | |
| SCHEMBL8364405 | 0.78 | KDM4E (0.55) | HPGDMITF | |
| SCHEMBL8366377 | 0.77 | CA12 (0.51) | PARP1CA12CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850235-B1 | QUINOLEIN-2(1H)-ONE DERIVATIVES AS SEROTONIN ANTAGONISTS | SANOFI SYNTHELABO (FR) | 1999-12-01 | — | — | EP | disclosed |
| US-5958924-A | HYPOTENSIVE AGENTS, CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS, RESTENOSIS, ANTICOALUGANTS, RESPIRATORY SYSTEM DISORDERS | SYNTHELABO (FR) | 1999-09-28 | — | — | US | disclosed |