SCHEMBL17505180

SCHEMBL17505180

CCCn1c(=O)ccc2cc(N)ccc21

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRPF1 P55201 3/20 0.63
PRKCI P41743 1/20 0.46
KDM4E B2RXH2 3/20 0.45
ALDH1A1 P00352 2/20 0.45
MAPT P10636 2/20 0.45
GAA P10253 1/20 0.45
GFER P55789 1/20 0.45
ADORA2B P29275 4/20 0.40
ADORA2A P29274 2/20 0.40
RAD52 P43351 1/20 0.39
ADORA1 P30542 1/20 0.37
POLB P06746 1/20 0.37
MEN1 O00255 1/20 0.37
HPGD P15428 1/20 0.37
MAPK1 P28482 1/20 0.37
HTT P42858 1/20 0.37
HBB P68871 1/20 0.37
KMT2A Q03164 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17576257 0.87 BRPF1 (0.62) BRPF1PRKCIKDM4EALDH1A1MAPT
SCHEMBL17979387 0.82 MAPT (0.45) BRPF1KDM4EMAPTADORA2BADORA2A
SCHEMBL17979482 0.81 BRPF1 (0.41) BRPF1KDM4EALDH1A1MAPTGAA
SCHEMBL22421744 0.79 BRPF1 (0.67) BRPF1PRKCIKDM4EALDH1A1MAPT
SCHEMBL17979340 0.78 BRPF1 (0.37) BRPF1KDM4EALDH1A1MAPTPOLB
SCHEMBL7085783 0.78 BRPF1 (1.00) BRPF1PRKCIKDM4EALDH1A1MAPT
SCHEMBL14279770 0.77 BRPF1 (0.54) BRPF1PRKCIKDM4EALDH1A1MAPT
SCHEMBL17505191 0.77 BRPF1 (0.48) BRPF1PRKCIKDM4EALDH1A1MAPT
SCHEMBL1490111 0.76 BRPF1 (0.53) BRPF1PRKCIKDM4EALDH1A1MAPT
SCHEMBL1052103 0.76 CA12 (0.58) BRPF1KDM4EALDH1A1MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3398940-B1 HIGH STRESS RESISTANT PLANT GROWTH REGULATOR AND PREPARATION METHOD AND USE THEREOF CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2022-06-22 EP disclosed
EP-3398940-B1 HIGH STRESS RESISTANT PLANT GROWTH REGULATOR AND PREPARATION METHOD AND USE THEREOF CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2022-06-22 EP disclosed
US-11076597-B2 High stress resistant plant growth regulator and preparation method and use thereof CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2021-08-03 US disclosed
US-11076597-B2 High stress resistant plant growth regulator and preparation method and use thereof CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2021-08-03 US disclosed
EP-3342766-B1 SMALL MOLECULE COMPOUND FOR ENHANCING PLANT STRESS RESISTANCE CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2020-12-09 EP disclosed
EP-3342766-B1 SMALL MOLECULE COMPOUND FOR ENHANCING PLANT STRESS RESISTANCE CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2020-12-09 EP disclosed
US-10842151-B2 Small molecule compound for enhancing plant stress resistance CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2020-11-24 US disclosed
US-10842151-B2 Small molecule compound for enhancing plant stress resistance CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2020-11-24 US disclosed
CN-106749044-B ABA analogue for enhancing plant stress resistance 中国科学院上海生命科学研究院 2020-04-21 CN disclosed
US-20190000084-A1 HIGH STRESS RESISTANT PLANT GROWTH REGULATOR AND PREPARATION METHOD AND USE THEREOF SHANGHAI INSTITUTES FOR BIOLOGICAL SCIENCES, CHINESE ACADEMY OF SCIENCES (CN) 2019-01-03 US disclosed
US-20190000084-A1 HIGH STRESS RESISTANT PLANT GROWTH REGULATOR AND PREPARATION METHOD AND USE THEREOF SHANGHAI INSTITUTES FOR BIOLOGICAL SCIENCES, CHINESE ACADEMY OF SCIENCES (CN) 2019-01-03 US disclosed
US-20180360039-A1 Small Molecule Compound for Enhancing Plant Stress Resistance CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2018-12-20 US disclosed
EP-3398940-A1 HIGH STRESS RESISTANT PLANT GROWTH REGULATOR AND PREPARATION METHOD AND USE THEREOF Shanghai Institutes For Biological Sciences, Chinese Academy Of Sciences (CN) 2018-11-07 EP disclosed
EP-3342766-A1 SMALL MOLECULE COMPOUND FOR ENHANCING PLANT STRESS RESISTANCE Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences (CN) 2018-07-04 EP disclosed
EP-3342766-A1 SMALL MOLECULE COMPOUND FOR ENHANCING PLANT STRESS RESISTANCE Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences (CN) 2018-07-04 EP disclosed
WO-2016022915-A1 6-SULFONYLAMINO QUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS THE REGENT OF THE UNIVERSITY OF CALIFORNIA (US) 2016-02-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190000084-A1 HIGH STRESS RESISTANT PLANT GROWTH REGULATOR AND PREPARATION METHOD AND USE THEREOF BOLA2; BOLA2B, MYB, PPA1 BRPF1 388/4885PRKCI 2422/4885KDM4E 1176/4885
US-11076597-B2 High stress resistant plant growth regulator and preparation method and use thereof BOLA2; BOLA2B, MYB, PPA1 BRPF1 388/4885PRKCI 2422/4885KDM4E 1176/4885
US-10842151-B2 Small molecule compound for enhancing plant stress resistance CYP4F11, RICTOR, MYB BRPF1 1596/4885PRKCI 2825/4885KDM4E 3723/4885
US-20180360039-A1 Small Molecule Compound for Enhancing Plant Stress Resistance CYP4F11, RICTOR, MYB BRPF1 1596/4885PRKCI 2825/4885KDM4E 3723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.