Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | SCN7A | Q01118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17979340 | 0.85 | BRPF1 (0.37) | BRPF1SCN7AMAPTKMT2ACCNB2 | |
| SCHEMBL17505180 | 0.81 | BRPF1 (0.63) | BRPF1SCN7AMAPTKMT2ACCNB2 | |
| SCHEMBL9320188 | 0.81 | BRPF1 (0.62) | BRPF1CA12CA1CA2CA3 | |
| SCHEMBL17979387 | 0.80 | MAPT (0.45) | BRPF1SCN7AMAPTCCNB2CCNE2 | |
| SCHEMBL19865855 | 0.77 | MAPT (0.44) | BRPF1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL1052103 | 0.74 | CA12 (0.58) | BRPF1CA12CA9MAPTKMT2A | |
| SCHEMBL29941844 | 0.74 | CA12 (0.58) | BRPF1CA12CA9MAPTKMT2A | |
| SCHEMBL20548890 | 0.74 | CYP1A2 (0.51) | MAPTKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL17979460 | 0.73 | ALDH1A1 (0.61) | BRPF1CA12CA1CA2CA9 | |
| SCHEMBL17979543 | 0.73 | MAPT (0.41) | BRPF1MAPTKMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107207440-B | 2-oxo-3, 4-dihydroquinoline compounds as plant growth regulators | 先正达参股股份有限公司 | 2020-11-10 | — | — | CN | disclosed |
| US-10392348-B2 | 2-oxo-3,4-dihydroquinoline compounds as plant growth regulators | SYNGENTA PARTICIPATIONS AG (CH) | 2019-08-27 | — | — | US | disclosed |
| EP-3256447-B1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-05 | — | — | EP | disclosed |
| US-20180044297-A1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-02-15 | — | — | US | disclosed |
| EP-3256447-A1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | Syngenta Participations AG (CH) | 2017-12-20 | — | — | EP | disclosed |
| WO-2016128317-A1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10392348-B2 | 2-oxo-3,4-dihydroquinoline compounds as plant growth regulators | CDC25B, OSR1, CDC25C | BRPF1 2161/4885CA12 4582/4885CA1 4131/4885 |
| US-20180044297-A1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | CDC25B, OSR1, CDC25C | BRPF1 2161/4885CA12 4582/4885CA1 4131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.