Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | NGFR | P08138 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17505187 | 0.88 | HSD17B10 (0.74) | HSD17B10HTTMAPTTSHRPARP1 | |
| SCHEMBL3116596 | 0.77 | HSD17B10 (0.53) | HSD17B10HTTMAPTPARP1KDM4E | |
| SCHEMBL12559597 | 0.77 | RAB9A (0.76) | HSD17B10HTTMAPTTSHRPARP1 | |
| SCHEMBL17505145 | 0.77 | ALDH1A1 (0.57) | HSD17B10HTTMAPTTSHRPARP1 | |
| SCHEMBL17505150 | 0.76 | HSD17B10 (0.50) | HSD17B10HTTMAPTTSHRPARP1 | |
| SCHEMBL17505189 | 0.75 | HSD17B10 (0.52) | HSD17B10HTTMAPTTSHRPARP1 | |
| SCHEMBL17505210 | 0.75 | ALDH1A1 (0.65) | HSD17B10HTTMAPTTSHRPARP1 | |
| SCHEMBL27532886 | 0.73 | KIF11 (0.50) | HSD17B10HTTMAPTTSHRPARP1 | |
| SCHEMBL31154597 | 0.72 | CYP2A6 (0.53) | HSD17B10MAPTTSHRPARP1KDM4E | |
| SCHEMBL1770840 | 0.72 | AR (0.55) | MAPTPARP1KDM4ECA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016022915-A1 | 6-SULFONYLAMINO QUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | THE REGENT OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-02-11 | — | — | WO | disclosed |