Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ARG1 | P05089 | 2/20 | 0.34 |
| ▸ | ARG2 | P78540 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21902870 | 0.99 | CYP1A2 (0.39) | SMN1; SMN2CYP1A2MAPK1ALDH1A1POLB | |
| SCHEMBL17506616 | 0.84 | ARG1 (0.34) | ARG1ARG2 | |
| SCHEMBL17850656 | 0.84 | GBA1 (0.37) | SMN1; SMN2 | |
| SCHEMBL21906658 | 0.83 | ARG1 (0.52) | ARG1ARG2 | |
| SCHEMBL21902875 | 0.83 | ARG1 (0.52) | ARG1ARG2 | |
| SCHEMBL22524568 | 0.82 | ARG1 (0.53) | SMN1; SMN2CYP1A2MAPK1ARG1ARG2 | |
| SCHEMBL4457915 | 0.82 | ARG1 (0.53) | SMN1; SMN2CYP1A2MAPK1ARG1ARG2 | |
| SCHEMBL21904645 | 0.82 | ARG1 (0.53) | SMN1; SMN2CYP1A2MAPK1ARG1ARG2 | |
| SCHEMBL17506595 | 0.80 | ARG1 (0.43) | CYP1A2ARG1ARG2 | |
| SCHEMBL17506694 | 0.78 | ARG1 (0.39) | ARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2632927-B1 | BORONATES AS ARGINASE INHIBITORS | MARS INC (US) | 2016-02-10 | — | — | EP | disclosed |